In the Women’s Health Initiative Memory Study, including 4,532 women 65 years of age and older, followed for an average of 4 years, 82% (n = 3,729) were 65 to 74 while 18% (n = 803) were 75 and over. Most women (80%) had no prior hormone therapy use. Women treated with conjugated estrogens plus medroxyprogesterone acetate were reported to have a 2-fold increase in the risk of developing probable dementia. Alzheimer’s disease was the most common classification of probable dementia in both the conjugated estrogens plus medroxyprogesterone acetate group and the placebo group. Ninety percent of the cases of probable dementia occurred in the 54% of women that were older than 70 (see WARNINGS: Dementia ).
Hi I had a hysterectomy about 30yrs ago I’m now 70 was on Premarin 625 two a day then one day then onto estradot 25 I have osteoporosis in my back and a few fingers have phlebitis in my legs get very bad headaches take like plus minus 100 syndols a month only thing that doesn’t make me nauses tried going off plasters I get to like 5 days I get flushes and like banging in my head like as if to say put the plaster back and I’m not crazy last year I felt bad and had every test there was and Doctor said I was fine want to stop plaster but would the rest of me just crumble I’m a small person weigh 61kg desperate for advise !!