According to the aggregate data from a number of scientific studies, despite its conservative nature, Primobolan was proven to provide significant increases in muscle development in a reasonable amount of time. Another interesting fact that was discovered during the testing of this compound was the fact that it effectively bound itself to the AR. In fact, Primobolan was able to bind itself to the AR more effectively than naturally produced testosterone. This is huge because the ability to effectively bind to the AR allows Primobolan to be one of the most effective fat-burning compounds available. Positive AR binding has been directly correlated with lipolysis.
The Oxandrolone hormone does not carry any estrogenic related side effects. It does not aromatize and cannot lead to gynecomastia or water retention due to increases in estrogen levels. It further carries no progestin related activity, which again supports no estrogenic related side effects. Due to water retention being impossible with this steroid, this will decrease the risk of high blood pressure. Excess water retention can promote high blood pressure. Some steroids that do not aromatize can lead to high blood pressure, such as Trenbolone , but Anavar is rarely associated with this trait.
Also, medical advice should be sought if the person has previously suffered heart attack, has a disease of the blood vessels or the heart, has high cholesterol levels in the blood, has clotting or excess bleeding problems, or has diabetes, kidney, or liver diseases. If the person has one or more of these problems, then an alteration of the dosage may be required. Medicines that can react with Winstrol are blood thinners or anticoagulants, diabetes medication, and insulin. Care should be taken while administering Winstrol with any of these medicines.