If you start to notice side effects, such as the beginning stages of gynecomastia, excessive water retention, or high blood pressure despite using anti-estrogen medications to prevent them, then your Deca Durabolin dosage is likely too high for your body. Just as you titrated your dose upward, begin to titrate back down if you notice these bothersome side effects. As an example, if you were taking four 100mg doses per week, use four 75mg doses per week, instead. This will shave 100mg per week off of your overall dose, and you should notice a difference. If not, go down to three 75mg doses per week.